Allantoin in Comfrey: Why It Matters for Skin Regeneration

Allantoin is one of the most important compounds responsible for comfrey’s long-standing reputation in topical care. While many modern skincare products contain synthetic allantoin, comfrey is one of the richest natural botanical sources of this compound.

Allantoin supports skin by encouraging cell turnover and regeneration, helping damaged or stressed skin return to a more balanced state. It is especially relevant in situations involving dryness, irritation, or recovery from minor skin trauma.

From a biochemical standpoint, allantoin stimulates fibroblast activity, which plays a key role in connective tissue repair. This mechanism helps explain why comfrey was historically used on bruises, sprains, and areas surrounding joint or bone stress.

📚 Staiger, C. (2012), Phytotherapy Research
https://doi.org/10.1002/ptr.4592

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Comfrey in Topical Skincare: Uses, Science, Safety & History